Wrinkles can be successfully treated with a protein called Botulinum Toxin . In Cosmetic use the amount of toxin used is small and extremely safe. The toxin reversibly weakens the muscles responsible for dynamic wrinkles which are lines that appear when you animate your face. Static wrinkles are lines that appear at rest; these do not usually improve with Botulinum Toxin and may be best treated with Dermal Fillers.